Horizyn: enzyme discovery with AI

Enzyme discovery in seconds

Online or via our API, Horizyn searches the biosphere to find catalysts for any chemistry. Enter SMILES, free text, a protein family or just draw. Get back a ranked list of enzymes with scored predictions, structures, and one-click docking.

The Chemistry you care about

Submit a reaction as SMILES, a UniProt accession, or a raw amino-acid sequence. Horizyn auto-detects the query type and parses half-reactions, cofactors, and protonation states through an interactive Reaction Builder.

Screen in under a second

For most industrially useful reactions, no enzyme has ever been characterised. Horizyn screens millions of enzymes for activity and expression.

Validated in the lab

Horizyn has been validated across dozens of real world contexts in vitro, and recently peer-reviewed in PNAS.